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Synthetic biology uses engineering principles to design and construct new devices and systems based on biological components (bacteria). Applications include the manufacture of biofuels and the development of smart therapeutics. Prof Meldrum and her team are currently competing in the 2013 International Genetic Engineered Machines (iGEM) competition against the world's leading universities. The Leeds iGEM team comprises undergraduate Biochemists, Nanotechnologists, Neurobiologists and Physicists. Their project uses live bacteria as sensors for lethal pathogens in water, with applications for clean water systems in developing countries.